Breastfeeding and Eating Nuts and Eggs For Infant Tolerance (BENEFIT) Trial
Not Applicable
Completed
- Conditions
- Inflammatory and Immune System - AllergiesFood Allergy
- Registration Number
- ACTRN12617001465347
- Lead Sponsor
- niversity of Western Australia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 109
Inclusion Criteria
Eligible participants will be women who are planning to breastfeed for at least 6 months. Infants to have at least two family members (mother, father or siblings) with medically diagnosed allergic disease (asthma, eczema, hay-fever or IgE mediated food allergy).
Exclusion Criteria
Women with egg or peanut allergies (<1% of adult population) will be excluded, as they would be unable to safely follow the intervention without an allergic reaction.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Egg-specific IgG4 concentrations in infant blood. These will be measured using the ImmunoCAP 250 system (Phadia AB, Uppsala, Sweden).[When Infant is 6 months of age.];Peanut-specific IgG4 concentrations in infant blood. These will be measured using the ImmunoCAP 250 system (Phadia AB, Uppsala, Sweden).[When infant is 6 months of age.]
- Secondary Outcome Measures
Name Time Method