The Intervention of Chinese Medicine on NETs Formation of Pneumonia Sepsis
Phase 1
Recruiting
- Conditions
- pneumonia sepsis
- Registration Number
- ITMCTR2100004797
- Lead Sponsor
- onghua Hospital Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
1. Meeting the diagnostic criteria of Sepsis3.0 and pulmonary infection;
2. Meeting the Chinese medicine criteria of stasis and toxin;
3. Aged 18-90 years;
4. Signing the informed consent file.
Exclusion Criteria
1. The lung tumor or pulmonary tuberculosis induced pulmonary infection;
2. The severe inhibition of immune system, for example, AIDS, chemoradiotherapy of tumor or rheumatic connective tissue disease;
3. Dying after admission within 24 hours;
4. Having allergic history of the medicine;
5. Gestation, preparing a pregnancy or suckling period;
6. Patients with mental disorder;
7. Unable to take Chinese medicine for any reasons;
8. Fasting for any reasons.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method APACHE II score;procalcitonin;circulating white blood count;C-reaction protein;
- Secondary Outcome Measures
Name Time Method chest X-ray;traditional Chinese medicine syndrome estimate;plasma NE-DNA;vital signs;coagulation function;oxygenation index;inflammation score;in-hospital mortality;mechanical ventilation;