Observation of genotype-phenotype interaction effects on white matter in Alzheimer Disease and Bipolar Disorder

Not Applicable

Completed

• Conditions: 1. Alzheimer Disease 2. Bipolar Disorder; Nervous System Diseases

• Registration Number: ISRCTN26135594
• Lead Sponsor: Hospital Santiago Apostol (Spain)

Brief Summary

2016 results in: https://www.ncbi.nlm.nih.gov/pubmed/26567744 2017 results in: https://www.ncbi.nlm.nih.gov/pubmed/28670271

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-01-27
• Study Completion: 2013-06-01
• Last Update Posted: 11 February 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

All participants:
1. Aged over 64 years
2. Fluency in Spanish

Alzheimer's Disease:
Participants must fulfil the NINDS-ADRDA criteria for probable Alzheimer's disease.

Bipolar Disorder:
Participants must fulfill the DSM-IV’s criteria for bipolar disorder.

Health Controls:
Participants must not have previous memory complaints.

Exclusion Criteria

Significant neurological disease other than AD and BD

Study & Design

• Study Type: Observational
• Study Design: Not specified