A study to compare the effect of different types of anaesthesia on blood inflammatory markers in gynaecological cancer patients.
Not Applicable
- Conditions
- Health Condition 1: C56- Malignant neoplasm of ovary
- Registration Number
- CTRI/2022/11/046961
- Lead Sponsor
- All India Institute of Medical Sciences Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Female patients aged between 25-75yrs (American society of anaesthesiologist grading I â?? III) undergoing surgery for gynaecological cancer will be included.
Exclusion Criteria
1.Patients not willing to participate in the study
2.ASA > III
3.Patient underwent previous surgery except diagnostic biopsy
4.Any contraindication to use of study drug
5.Any ongoing infection in patient
6.Any other chronic inflammatory condition as RA, inflammatory bowel disease etc.
7.Secondary sepsis and/or septic shock with an underlying condition
8.Active infection such as severe peritonitis, pancreatitis, or trauma
9.Long-term ICU stay
10.Pre Existing immunodeficiency.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â??To compare difference in change of post-operative and preoperative NLR (Day 3-preoperative) in both the groups.Timepoint: day 3
- Secondary Outcome Measures
Name Time Method To compare changes in level of post-operative and preoperative platelet lymphocyte ratio (PLR), monocyte lymphocyte ratio (MLR), mean platelet volume to platelet count ratio(MPV/PC), (Day 3-Preoperative) in both groups.Timepoint: Day 3