Study Evaluating a New Drug to Treat Participants with Eyelid Inflammation Related to a Parasite (Demodex)

Phase 2

Completed

• Conditions: Blepharitis; Blepharitis due to Demodex infestation; Eye - Diseases / disorders of the eye

• Registration Number: ACTRN12620000320954
• Lead Sponsor: Roberto González Salinas, MD

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-03-09
• Study Completion: 2020-05-06
• Last Update Posted: 24 November 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

Participants must meet all of the following criteria in at least one eye:
- More than 10 cylindrical dandruff present on the upper lid
- Mild to severe upper eyelid margin erythema
- Average Demodex density, upper and lower eyelids combined, of 1.5 mites or more per eyelash

Exclusion Criteria

- Systemic or topical antibacterial, antiparasitic or anti-inflammatory steroid treatment within the last 14 days
- Topical tea tree oil or hypochlorous acid treatment of the ophthalmic area within the last 14 days
- The use of lid hygiene products (eyelid scrubs) in the last 14 days or unwilling to forego the use of lid hygiene products during the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified