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Bioequivalency Study of Clarithromycin Tablets Under Fed Conditions

Not Applicable
Completed
Conditions
Infection
Registration Number
NCT00602498
Lead Sponsor
Roxane Laboratories
Brief Summary

The objective of this study was the bioequivalence of a potential generic 500 mg clarithromycin tablet formulation compared with Abbott Laboratories 500 mg clarithromycin tablet, Biaxin® following a single 500 mg dose, administered with food.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
28
Inclusion Criteria
  • No clinically significant abnormal findings on the physical examination, medical history, or clinical laboratory results during screening.
Exclusion Criteria
  • Positive test for HIV, Hepatitis B, or Hepatitis C.
  • Treatment with known enzyme altering drugs.
  • History of allergic or adverse response to clarithromycin or any other macrolide antibiotic.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
BioequivalenceBaseline, Two period, Seven day washout
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

MDS Pharma Services

🇺🇸

Phoenix, Arizona, United States

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