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Study to Investigate the Effect of Deferasirox on the Pharmacokinetics of Midazolam

Phase 1
Completed
Conditions
Healthy
Registration Number
NCT00427505
Lead Sponsor
Novartis
Brief Summary

This is a study to investigate the pharmacokinetics of deferasirox

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
22
Inclusion Criteria
  • Good health
  • No evidence of iron deficiency
  • Weight between 50 and 100 kg
  • Body Mass Index between 19 and 29 kg/m2
Exclusion Criteria
  • Use of certain drugs, herbal remedies or nutrients

Other protocol-defined inclusion/exclusion criteria may apply

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
To assess the effect of deferasirox on the pharmacokinetics of midazolam
Secondary Outcome Measures
NameTimeMethod
Safety assessed by adverse events (AEs)
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