Is Bifidobacterium breve effective in the treatment of childhood constipation?

• Conditions: constipation; stool problem; 10017977

• Registration Number: NL-OMON33537
• Lead Sponsor: Yakult Nederland B.V.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

At least 2 or more of the following criteria for at least 8 weeks:
1. Defecation frequency <3/week
2. Faecal incontinence >1/week
3. Large amount of stools which clog the toilet
4. Painful defecation
5. Withholding behaviour
6. Abdominal or rectal faecal impaction upon physical examination

Exclusion Criteria

1. Mental retardation/metabolic disease (hypothyroidism)
2. Hirschsprung's disease/ spinal abnomalies/ anorectal pathology
3. Children who underwent gastro-intestinal surgery
4. Children with functional non-retentive faecal incontinence
5. Use of laxatives two weeks prior to the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Defecation frequency</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Stool consistency<br /><br>- Pain during defecation<br /><br>- The frequency of faecal incontinence episodes<br /><br>- Adverse effects<br /><br>- Use of Bisacodyl</p><br>