Motor Development and Orthoses in Spinal Muscular Atrophy (SMA)

• Conditions: Spinal Muscular Atrophy

• Registration Number: NCT00961103
• Lead Sponsor: Arcispedale Santa Maria Nuova-IRCCS

Brief Summary

Spinal Muscular Atrophy (SMA) is neurodegenerative disease of anterior horn cells of spinal cord and represents the second more frequent pathology in childhood.

According to the age of onset and the maximum motor function the disorder is classified in 4 types. Patients with SMA II and SMA III often use orthoses to achieve postural and dynamic functions.

In this retrospective observational study the investigators describe the characteristics of sitting position, standing and walking correlated to type and time of orthoses used.

Detailed Description

We collect data from patients with SMA II and SMA III referred to UDGEE from jan. 1995 to dec. 2008.

We estimate to achieve informations about 50-70 patients.

Study Timeline

• Status Verified: 2009-08
• Study First Submitted: 2009-08-17
• Study First Submitted QC: 2009-08-17
• Last Update Submitted: 2009-08-17
• Study First Posted: 2009-08-18
• Last Update Posted: 2009-08-18
• Study Start: 2009-09
• Primary Completion: 2009-11
• Study Completion: 2009-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Clinical and genetics diagnosis of SMA II and SMA III

Exclusion Criteria

• N/A

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
time and percentage of sitting, standing, walking achievement in SMA II and SMA III	aug.2009- nov.2009

Secondary Outcome Measures

Name	Time	Method
characteristics and percentage of orthoses for postural sitting control , standing and walking in SMA II and SMA III	aug. 2009 - dec.2009

Trial Locations

Locations (1)

UDGEE Hospital S.Maria Nuova; 🇮🇹 Reggio Emilia, RE, Italy