Assessment of Motor Development Related to Use of Orthoses in SMA II and III
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- time and percentage of sitting, standing, walking achievement in SMA II and SMA III
Study Overview
Brief Summary
Spinal Muscular Atrophy (SMA) is neurodegenerative disease of anterior horn cells of spinal cord and represents the second more frequent pathology in childhood.
According to the age of onset and the maximum motor function the disorder is classified in 4 types. Patients with SMA II and SMA III often use orthoses to achieve postural and dynamic functions.
In this retrospective observational study the investigators describe the characteristics of sitting position, standing and walking correlated to type and time of orthoses used.
Detailed Description
We collect data from patients with SMA II and SMA III referred to UDGEE from jan. 1995 to dec. 2008.
We estimate to achieve informations about 50-70 patients.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Clinical and genetics diagnosis of SMA II and SMA III
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
time and percentage of sitting, standing, walking achievement in SMA II and SMA III
Time Frame: aug.2009- nov.2009
Secondary Outcomes
- characteristics and percentage of orthoses for postural sitting control , standing and walking in SMA II and SMA III(aug. 2009 - dec.2009)