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Clinical Trials/NCT03783247
NCT03783247
Unknown
Not Applicable

Pericapsular Nerve Group Block Versus Fascia Iliaca Block for Hip Arthroplasty: a Randomized Controlled Trial

Cairo University1 site in 1 country50 target enrollmentFebruary 15, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Post Operative Pain Management
Sponsor
Cairo University
Enrollment
50
Locations
1
Primary Endpoint
morphine consumption
Last Updated
7 years ago

Overview

Brief Summary

In this study, the investigator will examine the efficacy of Pericapsular nerve group (PENG) block in hip surgeries as a post-operative pain management technique in comparison with fascia Iliaca block in hip surgeries

Detailed Description

Hip fracture is a common orthopedic emergency in the elderly, and it is associated with significant morbidity and mortality.1 Surgical reduction and fixation are the definitive treatment in most patients.2 Effective perioperative analgesia that minimizes the need for opioids and related adverse effects (such as delirium) is essential in this patient population. Regional analgesic techniques, including femoral nerve (FN) block, fascia iliaca block (FIB), and 3-in-1 FN block, are popular analgesic strategies, due mainly to their opioid-sparing effects and reduction in opioid-related adverse effects. The effect size of analgesia from these blocks is only moderate, and literature suggests that the obturator nerve (ON) is not covered. The anterior hip capsule is innervated by the ON, accessory obturator nerve (AON), and FN as reported by previous anatomic studies. The anterior capsule is the most richly innervated section of the joint, suggesting these nerves should be the main targets for hip analgesia. A recent anatomical study by Short et al15 confirmed the innervation of the anterior hip by these 3 main nerves but also found that the AON and FN play a greater role in the anterior hip innervation than previously reported. This study also identified the relevant landmarks for those articular branches. The high articular branches from FN and AON are consistently found between the anterior inferior iliac spines (AIIS) and the iliopubic eminence (IPE), whereas the ON , close to the inferomedial acetabulum. Using this information, the investigator developed an ultrasound-guided technique for blockade of these articular branches to the hip, the PENG (PEricapsular Nerve Group) block. In this study, the investigator will examine the efficacy of PENG block in hip surgeries as a post-operative pain management technique in comparison with fascia Iliaca block in hip surgeries

Registry
clinicaltrials.gov
Start Date
February 15, 2019
End Date
June 20, 2019
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Hassan Mohamed Ali

associate professor

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Patients scheduled for hip replacement surgeries e.g. hip hemiarthroplasty, total hip arthroplasty under subarachnoid block (SAB)

Exclusion Criteria

  • Coagulopathy
  • infection at the injection site
  • allergy to local anesthetics
  • severe cardiopulmonary disease (≥ASA IV)
  • diabetic or other neuropathies
  • patients receiving opioids for chronic analgesic therapy
  • contraindication to spinal anesthesia
  • inability to comprehend visual analog scale (VAS).

Outcomes

Primary Outcomes

morphine consumption

Time Frame: 24 hours

total morphine consumption over 24 hours

Secondary Outcomes

  • muscle power(24 HOURS)
  • pain scale Visual analogue Scale(24hours)

Study Sites (1)

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