Ginsenoside Improve Metabolic Syndrome

Not Applicable

• Conditions: Metabolic Syndrome

• Registration Number: NCT02034136
• Lead Sponsor: CHA University

Brief Summary

Aim : Investigated the effects of Korean red ginseng supplementation on metabolic parameters such as cholesterol, blood pressure and glucose.

Randomized Control Trial.

Detailed Description

Methods : A randomized, double-blind, placebo-controlled, single-center study in 60 subjects who are not taking drugs that could affect metabolic and vascular function. Subjects will be randomized into a Korean red ginseng (3.0g/d) group or placebo group for a 4-week study.

We will collect anthropometric measurements, blood for laboratory testing, inflammatory marker, hormones and mitochondrial DNA copy number.

Subject : Older than 40 years of age, presented with metabolic syndrome. Subjects were excluded if they were taking drugs that could affect metabolic and vascular function, including BP control drug, anti-diabetic drugs and lipid-lowering drugs.

Measurement : We will collect anthropometric measurements and blood for laboratory testing at the initial(week 0) and final (week 4)visits. Serum levels of blood glucose, insulin, total cholesterol, HDL-cholesterol,triglyceride, and DNA copy number of mitochondria.

Study Timeline

• Study First Submitted: 2013-07-21
• Status Verified: 2014-01
• Study First Submitted QC: 2014-01-10
• Last Update Submitted: 2014-01-10
• Study First Posted: 2014-01-13
• Last Update Posted: 2014-01-13
• Study Start: 2014-02
• Primary Completion: 2014-09
• Study Completion: 2014-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• metabolic syndrome

Exclusion Criteria

• Taking drug for lipid-lowering, BP control and anti-diabetic.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change from baseline in metabolic syndrome profile at week 4	Baseline and 4 weeks from intake of Ginsenoside	Total cholesterol, HDL-Cholesterol, Glucose, Blood Pressure, Body weight

Secondary Outcome Measures

Name	Time	Method
Change from baseline in hormones at week 4.	Initial and 4 weeks later	insulin ,cortisol, testosterone, somatomedin-c and DHEAS

Trial Locations

Locations (1)

Bundang CHA Hospital; 🇰🇷 Seoul, Kyeonggi-do, Korea, Republic of