Effects of Ginsenoside Supplementation on Insulin Resistance and Cardiometabolic Risk Factors in Men With Metabolic Syndrome: a Randomized Controlled Trial.
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Change from baseline in metabolic syndrome profile at week 4
研究概览
简要总结
Aim : Investigated the effects of Korean red ginseng supplementation on metabolic parameters such as cholesterol, blood pressure and glucose.
Randomized Control Trial.
详细描述
Methods : A randomized, double-blind, placebo-controlled, single-center study in 60 subjects who are not taking drugs that could affect metabolic and vascular function. Subjects will be randomized into a Korean red ginseng (3.0g/d) group or placebo group for a 4-week study.
We will collect anthropometric measurements, blood for laboratory testing, inflammatory marker, hormones and mitochondrial DNA copy number.
Subject : Older than 40 years of age, presented with metabolic syndrome. Subjects were excluded if they were taking drugs that could affect metabolic and vascular function, including BP control drug, anti-diabetic drugs and lipid-lowering drugs.
Measurement : We will collect anthropometric measurements and blood for laboratory testing at the initial(week 0) and final (week 4)visits. Serum levels of blood glucose, insulin, total cholesterol, HDL-cholesterol,triglyceride, and DNA copy number of mitochondria.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •metabolic syndrome
排除标准
- •Taking drug for lipid-lowering, BP control and anti-diabetic.
研究组 & 干预措施
Dietary fiber fill
Dietary fiber fill manufactured to mimic Ginsenoside tablet
干预措施: Dietary fiber fill (Dietary Supplement)
Ginsenoside
Ginsenoside :
Intervention : ginsenoside, 3 gram / day, for 28 days in intervention group
干预措施: Ginsenoside (Dietary Supplement)
结局指标
主要结局
Change from baseline in metabolic syndrome profile at week 4
时间窗: Baseline and 4 weeks from intake of Ginsenoside
Total cholesterol, HDL-Cholesterol, Glucose, Blood Pressure, Body weight
次要结局
- Change from baseline in hormones at week 4.(Initial and 4 weeks later)
研究者
Dong-Hyuk Jung
Assistant professor, Family medicine
CHA University