Factors Predict Difficult Colonoscopy Before the Procedure: Prospective Registry Study

Completed

• Conditions: Colonoscopy

• Registration Number: NCT06151275
• Lead Sponsor: Sisli Hamidiye Etfal Training and Research Hospital

Brief Summary

In this study, the investigators aim to evaluate the relationship between cecal intubation time during colonoscopies and factors such as the patient's age, body mass index, history of constipation, Wexner constipation score, antidepressant use, and previous abdominal surgery. The objective is to assess factors that may predict longer cecal intubation times, especially in difficult colonoscopies. Prior to the procedure, informed consent will be obtained from patients scheduled for colonoscopy in the surgical endoscopy unit, and relevant information will be recorded. During the procedure, data will be collected, including cecal intubation time, if ileal intubation is performed, and the total procedure time.

Detailed Description

This study is designed as a prospective single-center registry study and has been approved by the Ethics Committee of Sisli Hamidiye Etfal Training and Research Hospital on May 30, 2023. The inclusion criteria for study involve patients scheduled for colonoscopy in surgical endoscopy unit who have not undergone colorectal surgery. Following informed consent obtained from patients before colonoscopy, data forms prepared by investigators will be completed, evaluating patients' age, height, weight, body mass index, colonoscopy indication, antidepressant use, and history of abdominal surgeries. Additionally, the Wexner constipation score will be calculated for each patient.

The time taken to reach the cecum and, if intubated, the ileum, from the initial insertion of the endoscope in colonoscopy, as well as the total procedure time, will be recorded using a chronometer. Patients with inadequate bowel preparation preventing cecal intubation will be excluded from the study. The collected data will be analysed to assess factors prolonging cecal intubation time and, if possible, to identify predictors for difficult colonoscopy before procedure.

Study Timeline

• Study Start: 2023-06-07
• Study First Submitted: 2023-11-21
• Study First Submitted QC: 2023-11-21
• Study First Posted: 2023-11-30
• Status Verified: 2024-04
• Primary Completion: 2024-04-03
• Study Completion: 2024-04-03
• Last Update Submitted: 2024-04-03
• Last Update Posted: 2024-04-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 915

Inclusion Criteria

• 18-95 years old, admitted for colonoscopy

Exclusion Criteria

• Colonic resection history

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cecal intubation rate	During the colonoscopy	The rate of reaching the cecum in all colonoscopies performed
Ileal intubation rate	During the colonoscopy	The rate of reaching the terminal ileum in all colonoscopies performed
Cecal intubation time	During the colonoscopy	Time for reaching caecum starting from endoscope insertion, this time will recorded by chronometer and recorded as minutes
Ileal intubation time	During the colonoscopy	Time for reaching ileum starting from endoscope insertion, this time will recorded by chronometer and recorded as minutes

Secondary Outcome Measures

Name	Time	Method
Adenoma detection rate	During the colonoscopy	The rate at which endoscopists find one or more adenoma during colonoscopies

Trial Locations

Locations (1)

Sisli Hamidiye Etfal Research and Training Hospital; 🇹🇷 Istanbul, Turkey