The Association Between Uremic Toxins and Outcomes and Comorbidities in Patients With CKD
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- all cause mortality
研究概览
简要总结
The aim of this cohort study is:
To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.
详细描述
To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age ≥18 years old;
- •clinically diagnosed with chronic kidney disease, according K/DOQI criteria.
排除标准
- •acute kidney injury
- •history of kidney injury <3 months
- •malignancy
- •pregnancy
- •incomplete clinical data
结局指标
主要结局
all cause mortality
时间窗: 5 years
次要结局
- comorbidities(5 years)
研究者
Ding Feng
Director of Devision of Nephrology
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University