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Clinical Trials/NCT05491798
NCT05491798RecruitingNot Applicable

A Big Data-based Cohort Study for Cataract Patients

Sun Yat-sen University1 site in 1 country1,000 target enrollmentStarted: July 1, 2020Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Sponsor
Enrollment
1,000
Locations
1
Primary Endpoint
Change of best corrected visual acuity

Study Overview

Brief Summary

Cataract is an important cause of blindness and visual impairment worldwide. At present, the only effective treatment method is surgery. The visual function of most patients can be significantly improved after surgery, but there are still 5-20% of patients whose visual function cannot be improved after surgery. Previous studies have found that the surgical complications and postoperative visual function of cataract patients are closely related to the condition of the fundus, but the current fundus camera cannot perform clear fundus imaging of cataract patients, and the existing potential visual inspections, such as retinal visual inspection, are also inaccurate. Predict postoperative visual acuity. Therefore, there is an urgent need for a reliable postoperative effect prediction system for cataract patients to provide reference for both ophthalmologists and patients.

This study intends to collect patient medical record information and traditional/ultra-wide fundus photos and other multi-modal data. Firstly, this study will use artificial intelligence technology to enhance fundus photos of cataract patients to obtain clearer fundus photos. Then this study will use both medical record information and traditional/ultra-wide fundus photographs to predict postoperative vision and visual function of cataract patients.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Candidates for cataract surgery (phacoemulsification and intraocular lens implantation) within a week.

Exclusion Criteria

  • Unwilling or unable to receive fundus photography

Outcomes

Primary Outcomes

Change of best corrected visual acuity

Time Frame: Baseline and 1 week after surgery

Change of best corrected visual acuity from baseline to 1 week after surgery

Accuracy for detection of retinal disorders

Time Frame: 1 week after surgery

Accuracy for detection of retinal disorders using enhanced fundus images

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Sun Yat-sen University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Haotian Lin

Clinical Professor

Sun Yat-sen University

Study Sites (1)

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