The effect of quercetin on dermatitis caused by radiotherapy in breast cancer

Phase 3

Conditions: Dermatitis.
Acute radiodermatitis
L58.0

Registration Number: IRCT20230509058138N1

Lead Sponsor: Babol University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Female

Target Recruitment: 92

Inclusion Criteria

women with breast cancer who are between 30 to 70 years old
they underwent breast lumpectomy surgery
after 3-4 weeks of surgury, they came for radiotherapy

Exclusion Criteria

patients who have an underlying disease and a history of skin inflammation
patients who are in stage 4 or are undergoing radiotherapy for palliation
patients with Modified Radical Mastectomy must not be included in the study.
Patients with a history of severe allergy

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of radiotherapy-induced dermatitis according to RTOG classification. Timepoint: The severity of radiation dermatitis is evaluated once a week from the time of entering the study until the completion of the radiotherapy treatment. Method of measurement: Based on the criteria of Radiation Therapy Oncology Group.

Secondary Outcome Measures

Name	Time	Method
The time which symptoms of dermatitis develop. Timepoint: Once a week from the beginning of the study to the end of the radiotherapy duration. Method of measurement: We record the time when the symptoms of dermatitis developed in the weekly examination according to the opinion of the specialist who evaluates the patients.;Severity of patients' pain. Timepoint: Once a week from the beginning of the study to the end of the radiotherapy duration. Method of measurement: We record the change in pain intensity in the weekly examination according to the opinion of the specialist who evaluates the patients. The pain intensity of the patients is measured using the Visual Analogue Scale index.