Adverse Events in Acute Limb Ischemic Patient Undergoing Revascularization

• Conditions: Major Adverse Cardiac Events; Adverse Effect of Unspecified General Anesthetic

• Registration Number: NCT05362266
• Lead Sponsor: Mahidol University

Brief Summary

Acute limb ischemia is one of the devastating vascular emergencies that lead to life and limb loss if the appropriate treatment is not reached.The revascularization is a cornerstone in treating acute limb ischemia. The conventional surgical approach includes surgical embolectomy and surgical bypass.From the anesthetic aspect, this emergency condition limits the lengthening cardiovascular assessment of this high-risk patient group which might lead to the uncertainty outcome.With the variety of patients and procedures, we sought to find out the perioperative adverse events, especially major adverse cardiac events, in acute ischemic limb patients undergoing revascularization, in order to increase awareness of the team and properly admit to ICU in a retrospective manner.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-04-10
• Study First Submitted: 2022-04-11
• Status Verified: 2022-05
• Study First Submitted QC: 2022-05-03
• Last Update Submitted: 2022-05-03
• Study First Posted: 2022-05-05
• Last Update Posted: 2022-05-05
• Primary Completion: 2023-03-01
• Study Completion: 2023-04-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

• age more than 18 years
• undergoing revascularization surgery or procedure (surgical revascularization, endovascular revascularization, hybrid revascularization, catheter directed thrombolysis)

Exclusion Criteria

• incomplete data during perioperative period

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of major adverse cardiac events	during hospital stay, up to 4 weeks	Incidence of major adverse cardiac events, which are cardiovascular death, myocardial infarction, stroke

Secondary Outcome Measures

Name	Time	Method
Incidence of the perioperative complication	during hospital stay, up to 4 weeks	Incidence of the perioperative other complication, which are major bleeding, repercussion syndrome, compartment syndrome, rhabdomyolysis and unplanned ICU admission from any causes.
Factors contribute to the adverse outcome	during hospital stay, up to 4 weeks	Factors contribute to the adverse outcome, which are the patients' condition and the underlying diseases, the surgical intervention and the anesthetic technique.

Trial Locations

Locations (2)

Anesthesiology department, Siriraj Hospital, Mahidol University; 🇹🇭 Bangkok, Thailand

MahidolU; 🇹🇭 Bangkok, Thailand