Comparison of Clinical and Radiographic Evaluation of the Effect of Decalcified Freeze Dried Bone Allograft(DFDBA) with Amniotic Membrane and Decalcified Freeze Dried Bone Allograft(DFDBA) with Platelet Rich Fibrin(PRF) Membrane in the Treatment of Intrabony Defects in Periodontitis Patients
- Conditions
- Health Condition 1: null- Chronic Periodontitis patients with interproximal bone defects of 5mm or more
- Registration Number
- CTRI/2018/04/012987
- Lead Sponsor
- Geetika Prabhakar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1).Age group between 20-60years
2).Diagnosis with chronic periodontitis
3).Patients in good systemic health with no contraindication to periodontal surgery
4).Patients having Intrabony defects with pocket depths of >5mm and with radiographic evidence of vertical / angular bone loss in the affected sites.
5).Involved teeth to be vital and asymptomatic.
1).One â?? wall osseous defects.
2).Patients suffering from any systemic diseases or with compromised immune system.
3).Patients who had received any type of periodontal therapy for the past 6 months
4).Patients taking any immuno-suppressive drugs like corticosteroids
5).Patients with a known history of allergy to doxycycline or Chlorhexidine or any other medicine are used in the study.
6).Patients showing unacceptable oral hygiene compliance during / after the phase I therapy.
7).Patients taking any drug known to cause gingival enlargement.
8).Pregnant and/or lactating mothers.
9).Patients who were smokers or had tobacco in any other form.
10).Endodontically treated teeth.
11).Patient on anticoagulant therapy
12).Patient with bleeding disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Plaque Index (P.I.) (SILNESS AND LOE, 1964) <br/ ><br>2. Gingival Index (G.I.) (LOE &SILNESS, 1963). <br/ ><br>3. Probing Pocket Depth (PPD). <br/ ><br>4. Clinical Attachment Level (CAL). <br/ ><br>5.Radiographic Bone fill will be evaluated using intra oral periapical radiograph of the surgical site.Timepoint: clinical evaluation at baseline, 1 month, 3 months and 6 months after surgery. <br/ ><br>Radiographic evaluation at baseline, immediate post surgery and 6 months post surgery.
- Secondary Outcome Measures
Name Time Method 1. Plaque Index (P.I.) (SILNESS AND LOE, 1964) <br/ ><br>2. Gingival Index (G.I.) (LOE &SILNESS, 1963). <br/ ><br>3. Probing Pocket Depth (PPD). <br/ ><br>4. Clinical Attachment Level (CAL). <br/ ><br>5.Radiographic Bone fill will be evaluated using intra oral periapical radiograph of the surgical site.Timepoint: clinical evaluation at baseline, 1 month, 3 months and 6 months after surgery. <br/ ><br>Radiographic evaluation at baseline, immediate post surgery and 6 months post surgery.