Comparative study between the efficacy of Hyaluronic acid Gel and Advanced Platelet-Rich Fibrin in Post Extraction Sockets of Impacted Mandibular Third Molars .
Phase 1
Recruiting
- Conditions
- Generally healthy Patients aged more than 18 years old .Hyaluronic acid gel ,A-PRF, Third molars, wisdom teeth, Impacted third molar
- Registration Number
- TCTR20220602008
- Lead Sponsor
- Self funded
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 66
Inclusion Criteria
1.Patient aged more than 18 years old.
2. Horizontal and mesio angular impacted lower third molar teeth according to Winter classification that require bone removal from around the impacted teeth. Degree of impaction based on Pell & Gregory category (level A or B, class I or II).
Exclusion Criteria
Medically compromised patient:
1-Uncontrolled diabetic.
2-Coagulation disorders.
3-Immune compromised patient.
4-Patient treated with amino bisphosphate which affects bone metabolism.
5-Psychiatric problems.
6-Pregnant women.
7- Any medical condition that affects bone healing.
8- Heavy smokers (more than 20 cigarettes a day).
9.patients with distinct periapical pathology
10.Patients undergoing chemotherapy and radiotherapy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain, Swelling ,Trismus, Soft tissue healing first ,third and seventh days post operative pain by Visual analog scale, trismus by ruler ,soft tissue healing by Early wound healing
- Secondary Outcome Measures
Name Time Method /A N/A N/A