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Clinical Trials/NCT05908890
NCT05908890
Completed
Not Applicable

A Study to Determine the Efficacy of a Denture Adhesive Formulation to Seal Out Food Particles From Under the Mandibular Partial Denture

Procter and Gamble1 site in 1 country29 target enrollmentJuly 8, 2019
ConditionsPartial Denture

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Partial Denture
Sponsor
Procter and Gamble
Enrollment
29
Locations
1
Primary Endpoint
Poppy Seed Count Before Treatment Application
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The objective of this study is to evaluate the effectiveness of two denture adhesives at keeping food particles (seeds) from becoming trapped underneath partial denture(s).

Registry
clinicaltrials.gov
Start Date
July 8, 2019
End Date
October 3, 2019
Last Updated
2 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Procter and Gamble
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • give written informed consent prior to their participation;
  • be 18 years of age or older;
  • have a Kennedy Class I or class II partial mandibular denture with a minimum of three consecutive teeth on the prosthesis;
  • have a history of food particles getting under their partial, mandibular denture;
  • agree not to use any denture adhesive on the day of their study visits, prior to the visit;
  • agree to not participate in any other oral/dental product studies during the study;
  • be willing to use or not use denture adhesive as instructed during the treatment periods;
  • be willing to eat a poppy seed muffin;
  • be in good general health as determined by the Investigator/designee based on a review of the medical history/update; and
  • have a minimum of 4 total poppy seeds on their mandibular denture base and gingiva after eating the muffin.

Exclusion Criteria

  • present with any disease or conditions that could be expected to interfere with examination procedures or the subject's safe completion of the study;
  • self-report that they are allergic to denture adhesives or to the test food (gluten intolerance to muffin or intolerance to poppy seeds); or
  • have appliances with intracorneal attachments, crowns with precision attachments or implant overdentures:
  • have any condition or medication which, in the opinion of the investigator, is currently causing xerostomia.

Outcomes

Primary Outcomes

Poppy Seed Count Before Treatment Application

Time Frame: Immediately following consumption of the muffin before treatment application

Subjects ate 1/2 top of a poppy seed muffin. After eating the muffin, subjects were instructed to remove their partial mandibular denture and a dental professional counted the number of poppy seeds remaining on the subject's partial denture base and gingiva.

Poppy Seed Count After Treatment Application

Time Frame: Immediately following consumption of the muffin after treatment application

Subjects ate 1/2 top of a poppy seed muffin. After eating the muffin, subjects were instructed to remove their partial mandibular denture and a dental professional counted the number of poppy seeds remaining on the subject's partial denture base and gingiva.

Study Sites (1)

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