A phase II study of combination chemotherapy with carboplatin plus S-1 in advanced lung squamous cell carcinoma
- Conditions
- ung cancer
- Registration Number
- JPRN-UMIN000006983
- Lead Sponsor
- Hamamatsu University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Not provided
1) Patients who received previous treatment with the 5-FU 2) Patients who is contraindicated to administration of CBDCA and S-1 3) Patients with a history of the drug hypersensitivity 4) Patients with symptomatic metastases to brain 5) Uncontrolled massive pleural effusion, ascitic fluid and pericardial fluid retention case 6) Patients with watery diarrhea 7) Patients with serious complications 8) Patients with active concomitant malignancy 9) Patients with HBs antigen-positive or with HCV antibody-positive 10) Patients who uses flucytosine 11) Women with the pregnant possibility, a pregnancy or lactation and men with willing to get pregnant 12) Patients who were complicated with mental disease or neurologic manifestation, and it is judged that the participation in study is difficult 13) Any other cases who are regarded as inadequate for study enrollment by the investigator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Progression free survival
- Secondary Outcome Measures
Name Time Method Overall survival, 1-year survival Rate, Response Rate, Safety