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Clinical Trials/NCT05788861
NCT05788861
Recruiting
N/A

French Pediatric Nationwide Observatory of Invasive Group A Streptococcal Infection (in Childen for 0 to 18 Ages)

Association Clinique Thérapeutique Infantile du val de Marne1 site in 1 country100 target enrollmentSeptember 1, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Sepsis Due to Streptococcus, Group A
Sponsor
Association Clinique Thérapeutique Infantile du val de Marne
Enrollment
100
Locations
1
Primary Endpoint
Risk factors
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

This study is observational, retrospective and prospective study in pediatric patients hospitalized with invasive streptococcal A infection

Detailed Description

The main of this study is to identify and record cases of invasive and severe infections due to Streptococcus pyogenes. In order to evaluate the incidence of severe forms of disease and the possible contributing factors, and to optimize their management. Admitted patients to intensive care or critical care units in reported via Santé Publique France may also be included in this study. Secondly, epidemiological, clinical, bacteriological data of all severe or not cases, of group A Streptococcal infections will be compiled to describe their characteristics, and try to explain this recrudescence as well as possible.

Registry
clinicaltrials.gov
Start Date
September 1, 2022
End Date
September 1, 2026
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Association Clinique Thérapeutique Infantile du val de Marne
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age\<18 years
  • Documented invasive Group A Streptococcus infection (identification of GAS in a normally sterile site or from another site in case of toxin shock or necrotizing dermo-hypodermatitis)

Exclusion Criteria

  • Opposition of the patient or his/her legal representative

Outcomes

Primary Outcomes

Risk factors

Time Frame: 1 year

description of underlying conditions

Complications

Time Frame: 1 year

what are the complications due to severe infection

Treatments used in routine care unit

Time Frame: 1 year

which treatments are used in routine care unit to treat the infection

Death

Time Frame: 1 year

Death Outcome during hospitalisation

Treatments provided in intensive care unit

Time Frame: 1 year

what treatments are used in intensive care unit to treat infection

Hospitalisation

Time Frame: 1 year

How long patient was hospitalised during this infection

Characterization of Group A Streptococcus strains

Time Frame: 1 year

Characterization of Group A Streptococcus strains by the CNR

Study Sites (1)

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