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Vancomycin-Associated Acute Kidney Injury: A Cross-Sectional Study From a Multi- Center in China

Conditions
Vancomycin
Staphylococcal Infections
Adverse Effect
Acute Kidney Injury
Cross-sectional Study
Interventions
Registration Number
NCT03456544
Lead Sponsor
Peking University First Hospital
Brief Summary

The objective of this study was to investigate the current situation of vancomycin (VAN)-associated acute kidney injury (VA-AKI) in China and identify the risk factors for VA-AKI, as well as to comprehensively examine the risk related to concurrent drug use. Further, the investigators assessed the outcomes of patients who developed VA-AKI and the risk factors for these outcomes. Finally, the investigators aimed to provide suggestions for improving the prevention and treatment of VA-AKI in China.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
10000
Inclusion Criteria
  • Using Vancomycin
  • ≥18 years old
Exclusion Criteria
  • Medical records were incomplete
  • Had been diagnosed with stage 5 CKD or were regularly receiving dialysis
  • SCr were not being adequately monitored to detect the development of AKI
  • Had undergone nephrectomy

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
VAN-AKIVancomycinPatients who had vancomycin associated acute kidney injury.
Primary Outcome Measures
NameTimeMethod
Vancomycin-associated acute kidney injury(VAN-AKI) occuration rate1 year
Secondary Outcome Measures
NameTimeMethod
VAN-AKI detection rate1 year
TDM detction rate1 year
0h Serum creatinine detction rate1 year
48h Serum creatinine detction rate1 year

Trial Locations

Locations (1)

Peking University First Hospital

🇨🇳

Beijing, Beijing, China

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