SCOOT: Sample Collection for DART
- Conditions
- Lung Cancer
- Registration Number
- NCT05368298
- Lead Sponsor
- University of Oxford
- Brief Summary
The study will use a blood sample collected from participants to:
* Develop new ways of finding and diagnosing lung health problems, such as lung cancer.
* Develop tools which make it easier to screen people with possible lung health problems, diagnose problems earlier and with fewer tests, and start the best treatment faster.
* Help improve the early diagnosis of lung cancer, as finding lung cancer early means that it can be treated more easily and successfully.
- Detailed Description
The results from this study will be linked with the data from the DART study (also collecting data through the Lung Health Check programme) to develop new ways of using computer technology (artificial intelligence) to improve lung health care. The studies use computer programs (called 'algorithms') which can be trained to analyse medical samples. Once developed, these algorithms can be used to support doctors by increasing their speed and accuracy of diagnosing issues.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 5000
- Patients with a pulmonary nodule or nodule(s) detected on a CT scan performed as part of Lung Cancer Screening from the Lung Health Check centres, that require further investigation with a PET-CT scan, and / or biopsy, and / or resection
- Willing and able to give informed consent
- None -
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To develop an algorithm that gives a greater than chance improved ability to diagnose lung cancer using the blood biomarkers with or without the AI CT algorithm compared to not using them by February 2025
- Secondary Outcome Measures
Name Time Method To develop an algorithm that gives a greater than chance improved ability to diagnose lung cancer using the blood biomarkers with or without the AI CT and blood markers algorithm compared to not using them by February 2025
Trial Locations
- Locations (10)
Lung Health Check Centre: Royal Sussex
🇬🇧Brighton, United Kingdom
Lung Health Check Centre: Gateshead
🇬🇧Gateshead, United Kingdom
Lung Health Check Centre: Stoke
🇬🇧Stoke, United Kingdom
Lung Health Check Centre: North Bristol
🇬🇧Bristol, United Kingdom
Lung Health Check Centre: Corby & Kettering
🇬🇧Kettering, United Kingdom
Lung Health Check Centre: Cheshire & Merseyside
🇬🇧Liverpool, United Kingdom
Lung Health Check Centre: Plymouth
🇬🇧Plymouth, United Kingdom
Lung Health Check Centre: Newcastle & Gateshead
🇬🇧Newcastle, United Kingdom
Lung Health Check Centre: South Tyneside and Sunderland
🇬🇧Sunderland, United Kingdom
Lung Health Check Centre: RM Partners
🇬🇧London, United Kingdom