Prevalence of Hypomagnesaemia after Major Abdominal Surgery (Magmas-I Study)

Not Applicable

• Conditions: magnesium deficiency; hypomagnesemia post major abdominal surgery; Surgery - Other surgery; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12620000913976
• Lead Sponsor: Dr Aihua Wu

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-09-16
• Last Update Posted: 21 September 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Inclusions (must meet all of the following three criteria):
1.Adult patients undergoing elective laparoscopic or open abdominal surgery at Angliss Hospital and Maroondah Hospital, Eastern Health
2.Surgery must last more than two hours
3.Patients must stay in the hospital for more than one night

Exclusion Criteria

Exclusions:
1. Patient refusal
2. younger than 18 years old
3. Language barrier
4. Intellectual disability or dementia

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To establish a baseline prevalence of hypomagnesemia before and after major abdominal surgery:<br>Normal serum magnesium levels are between 1.8 and 2.2 mg/dL. Hypomagnesemia is an electrolyte disturbance caused when there is a low level of serum magnesium (less than 1.8 mg/dL) in the blood.<br>Through the routine preoperative blood tests, preoperative and postoperative day-1 serum magnesium levels will be measured. These results will be accessed from the hospital electronic medical records. <br>The prevalence will be calculated by the percentage of patients whose magnesium levels are lower than 1.8 mg/dL. Since this is observational study, i.e., no intervention or treatment, this prevalence is a baseline.[preoperative blood tests are usually performed when the patients attend the pre-admission clinic;<br>postoperative blood tests will be performed on the next morning after surgery, i.e., postoperative day-1<br>approximately two days in total from pre-operation to postoperative day-1]

Secondary Outcome Measures

Name	Time	Method
To determine the prevalence of severe hypomagnesemia before and after major abdominal surgery:<br>hypomagnesemia is defined as the serum magnesium lower than 1.8 mg/dL;<br>severe hypomagnesemia is defined as magnesium level below 1.25 mg/dL.<br>blood tests will be performed before and after surgery, data on serum magnesium results will be collected from the hospital electronic medical records.<br>the percentage of patients whose magnesium levels are lower than 1.25 mg/dL will be calculated, and the prevalence of severe hypomanesemia is thus determined.[preoperative blood tests are usually performed when the patients attend the pre-admission clinic;<br>postoperative blood tests will be performed on the next morning after surgery, i.e., postoperative day-1<br>approximately two days in total from pre-operation to postoperative day-1]