Effect of Iron-fortified Pea Powder on Exercise Performance

Not Applicable

Completed

• Conditions: Iron-deficiency
• Interventions: Dietary Supplement: Placebo (maltodextrin); Dietary Supplement: Regular pea powder; Dietary Supplement: Low phytate pea powder

• Registration Number: NCT04872140
• Lead Sponsor: University of Saskatchewan

Brief Summary

Female endurance athletes are susceptible to iron deficiency and this can impact their exercise performance. This study assesses the impact of an pea protein supplement with high iron bio-availability on iron status and exercise performance.

Detailed Description

Female endurance athletes are susceptible to iron deficiency due to poor iron intake from diets or possibly because of destruction of red blood cells during foot-strike hemolysis. This study will evaluate the impact of 8-weeks of iron supplementation through consumption of a pea-protein power that has high iron bio-availability due to low phytate levels. This will be compared to consumption of regular iron protein powder and maltodextrin placebo by randomizing participants to three groups. Participants will be assessed at baseline and after 8 weeks of supplementation for exercise performance (maximal aerobic capacity and a 5 km time trial running test), blood levels of ferritin and hemoglobin, and body composition (fat mass and lean tissue mass).

Study Timeline

• Study First Submitted: 2021-04-23
• Study First Submitted QC: 2021-05-02
• Study Start: 2021-05-03
• Study First Posted: 2021-05-04
• Primary Completion: 2022-06-30
• Study Completion: 2022-08-15
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-11
• Last Update Posted: 2022-10-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

• Female
• Regularly participate in aerobic endurance training

Exclusion Criteria

• Any contra-indications to exercise testing as determined with the "Get Active Questionnaire"

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo	Placebo (maltodextrin)	Placebo (maltodextrin) powder (0g iron per day)
Pea powder	Regular pea powder	Pea powder with normal phytate levels (7mg iron per day)
Pea power with high iron bio-availability	Low phytate pea powder	Pea powder with low phytate levels to increase iron bio-availability (7mg iron per day)

Primary Outcome Measures

Name	Time	Method
Change from baseline in ferritin levels	Up to 8 weeks	blood ferritin levels

Secondary Outcome Measures

Name	Time	Method
Change from baseline in hemoglobin levels	Up to 8 weeks	Blood hemoglobin concentration
Change from baseline in lean tissue mass	Up to 8 weeks	Lean tissue mass (kg) measured with dual energy X-ray absorptiometry
Change from baseline in maximal aerobic capacity	Up to 8 weeks	Maximal aerobic capacity (mL/kg/min) measured on a treadmill
Change from baseline in exercise time trial performance	Up to 8 weeks	Time (minutes) to complete 5 km running on a treadmill
Change from baseline in fat mass	Up to 8 weeks	Fat mass (kg) measured with dual energy X-ray absorptiometry

Trial Locations

Locations (1)

University of Saskatchewan; 🇨🇦 Saskatoon, Saskatchewan, Canada