Skin Efficacy Testing of Astrion Products

Not Applicable

Completed

• Conditions: Skin Pigment; Skin Red

• Registration Number: NCT06657352
• Lead Sponsor: Chia Nan University of Pharmacy ＆ Science

Brief Summary

This project aims to conduct safety and efficacy tests on the skin for the ingestion of Astrion Vitality Capsules, containing A. membranaceus and C. Asiatica roots, and the topical application of Astrion Vitality Cream. The goal is to develop health and skincare products that regulate physiological functions, promote overall wellness, and enhance skin beauty.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-11-28
• Primary Completion: 2023-09-30
• Study Completion: 2023-09-30
• Status Verified: 2024-10
• Study First Submitted: 2024-10-23
• Study First Submitted QC: 2024-10-23
• Last Update Submitted: 2024-10-23
• Study First Posted: 2024-10-24
• Last Update Posted: 2024-10-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Subjects aged ≥18 years.

Exclusion Criteria

• Non-voluntary participants.
• Subjects diagnosed with skin diseases, cirrhosis, or chronic renal failure by a -physician.
• Individuals with known allergies to cosmetics, drugs, or food.
• Pregnant or breastfeeding women.
• Individuals taking medication for chronic diseases.
• Subjects who, within 12 weeks prior to the test, have undergone laser facial treatments, chemical peels, or experienced prolonged sun exposure (more than 3 hours of direct sunlight in a week).
• Students taught by the investigator.
• Individuals unwilling to allow the publication of photos of the experimental results.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
skin melanin	The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit	Skin elastometer (Soft Plus) was utilized to measure skin melanin. Units: arbitrary units
Skin brightness	The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit	Skin color difference analyzer (Chroma Meter MM500) was utilized to measure skin brightness
skin moisture	The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit	Skin moisture meter (Corneometer CM825) was utilized to measure skin moisture. Units: arbitrary units
skin elasticity	The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit	Skin elastometer (Soft Plus) was utilized to measure skin elasticity. Units: arbitrary units
collagen density content	The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit	Subcutaneous collagen scanner (DermaLab® Series SkinLab Combo) was utilized to measure skin collagen. Units: arbitrary units
skin surface topography	The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit	VISIA Micro-Analysis Skin Image Analyzer was utilized to measure skin texture. Units: arbitrary units

Trial Locations

Locations (1)

Chia Nan University of Pharmacy ＆ Science; 🇨🇳 Tainan, Taiwan