MedPath

Reducing Duration of Untreated Psychosis Through Rapid Identification and Engagement

Not Applicable
Terminated
Conditions
Psychotic Disorders
Interventions
Other: Clinic based Engagement (Phase 2)
Other: Electronic Screen + Education (Phase 1)
Other: Community Mobile Engagement (Phase 2)
Other: Targeted Provider Education (Phase 1)
Registration Number
NCT02841956
Lead Sponsor
University of California, Davis
Brief Summary

Reducing Duration of Untreated Psychosis (DUP) is a primary goal for improving long-term outcomes in young people with a first episode of psychosis (FEP). The "standard of FEP care" within the US focuses on targeted provider education regarding signs and symptoms of early psychosis to motivate patient referrals to FEP services, followed by initiation of services within largely clinic-based settings Experience at the Early Diagnosis and Preventive Treatment (EDAPT) FEP specialty program at U.C. Davis in Sacramento has identified two important bottlenecks to reducing DUP, consistent with reports in the literature from other FEP clinics. These are 1) delays in the identification of psychotic symptoms by referral sources, and 2) delays or disruptions of patient engagement in specialty FEP care. Building upon a comprehensive and established referral network of 20 sites across the Sacramento area (schools/universities, ER/inpatient hospitals, outpatient mental health, primary care), the investigators will address delays in patient identification and engagement using a two-phase, cluster randomized design. The investigators will consecutively test the impact of two interventions to reduce DUP, defined in this RFA as time from first onset of psychotic symptoms to engagement in FEP specialty care. To address identification delays, the investigators will examine the use of standard targeted provider education plus novel technology-enhanced screening compared to standard targeted provider education alone, testing the hypothesis that the education plus technology-enhanced screening will identify more patients, earlier in their illness. To address engagement delays, the investigators will compare the use of a mobile community-based, telepsychiatry-enhanced engagement team to standard clinic-based procedures for intake, engagement and initiation of treatment, to test the hypothesis that the mobile approach facilitates earlier and more stable engagement, thereby reducing DUP. The proposed work will provide new specific evidence-based practices for reducing DUP and improving outcomes through specialty care of individuals with a first episode of psychosis.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
427
Inclusion Criteria

Not provided

Read More
Exclusion Criteria

Not provided

Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Clinic based Engagement (Phase 2)Clinic based Engagement (Phase 2)Clinical intake interviews take place at the EDAPT clinic.
Electronic Screen + Education (Phase 1)Electronic Screen + Education (Phase 1)Electronic screening of participants and targeted education of providers according to standard EDAPT model.
Community Mobile Engagement (Phase 2)Community Mobile Engagement (Phase 2)Clinical intake interviews take place via videoconference at a location in the community convenient for the participant.
Targeted Provider Education (Phase 1)Targeted Provider Education (Phase 1)Targeted education of providers according to standard EDAPT model.
Primary Outcome Measures
NameTimeMethod
Days of active psychosis between onset of illness and identification for care (Duration of untreated psychosis)Day 1
Secondary Outcome Measures
NameTimeMethod
Rates of patient enrollment in first episode psychosis careBaseline

Trial Locations

Locations (1)

University of California Davis Early Diagnosis and Preventative Treatment (EDAPT) Clinic

🇺🇸

Sacramento, California, United States

© Copyright 2025. All Rights Reserved by MedPath