Comparing effect of intranasal Remifentanil with intranasal Dexmedetomidine on heart rate and blood pressure after tracheal intubatio

Phase 3

Recruiting

• Conditions: Intubation.; Failed or difficult intubation; T88.4

• Registration Number: IRCT20130311012782N60
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 186

Inclusion Criteria

Patients aged 18 to 65 years
Requires general anesthesia (laryngoscopy and intubation).
Agree to participate in the study
Patients with ASA 1 and 2

Exclusion Criteria

Airway malformation
Allergy to the studied drugs
Prolongation of the laryngoscopy process for more than 15 seconds
More than one attempt at intubation
Dissatisfaction of patients and requests to withdraw from the study in any of the work steps.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood pressure. Timepoint: Before laryngoscopy and at 1, 3, 5 and 10 minutes after. Method of measurement: sphigmomanometer.;Heart bit. Timepoint: Before intubation and at 1, 3, 5 and 10 minutes after. Method of measurement: Pulse oximeter.;Blood oxygen saturation percentage. Timepoint: Before intubation and at 1, 3, 5 and 10 minutes after. Method of measurement: Pulse oximeter.

Secondary Outcome Measures

Name	Time	Method
aryngoscopy time. Timepoint: During tracheal intubation. Method of measurement: Calculation of the time interval from the beginning to the end of tracheal intubation.;Amount of drugs received for hemodynamic stability of the patient. Timepoint: From the start of tracheal intubation to the time of exit from recovery. Method of measurement: Through registration in the patient file.