Comparing effect of intranasal Remifentanil with intranasal Dexmedetomidine on heart rate and blood pressure after tracheal intubatio
Phase 3
Recruiting
- Conditions
- Intubation.Failed or difficult intubationT88.4
- Registration Number
- IRCT20130311012782N60
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 186
Inclusion Criteria
Patients aged 18 to 65 years
Requires general anesthesia (laryngoscopy and intubation).
Agree to participate in the study
Patients with ASA 1 and 2
Exclusion Criteria
Airway malformation
Allergy to the studied drugs
Prolongation of the laryngoscopy process for more than 15 seconds
More than one attempt at intubation
Dissatisfaction of patients and requests to withdraw from the study in any of the work steps.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms by which intranasal Remifentanil and Dexmedetomidine modulate heart rate and blood pressure post-tracheal intubation?
How does the efficacy of intranasal Remifentanil compare to standard-of-care agents like Fentanyl in managing hemodynamic changes after laryngoscopy?
Which biomarkers could predict differential responses to intranasal Dexmedetomidine versus Remifentanil in patients with difficult intubation (T88.4)?
What are the potential adverse events associated with intranasal administration of Remifentanil and Dexmedetomidine in phase III trials for intubation management?
How do combination approaches of Remifentanil with other anesthetics compare to intranasal Dexmedetomidine in mitigating post-intubation hypertension and tachycardia?