Increasing Human Papillomavirus Vaccine Uptake in Low-Income, Ethnic Minority Adolescents in Los Angeles County
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 53,414
- Locations
- 2
- Primary Endpoint
- HPV Vaccine Uptake
Study Overview
Brief Summary
The primary aim of the project is to increase human papillomavirus (HPV) vaccine receipt rates among low-income, ethnic minority adolescents (girls and boys 11-17 years of age) in Los Angeles County. We will accomplish this goal by implementing and rigorously evaluating interventions in multiple venues that serve our target population, including the Los Angeles County Department of Public Health (LACDPH) and two large Federally Qualified Health Centers (FQHCs).
Our hypotheses are:
Primary hypothesis:
- The intervention group will have a higher rate of HPV vaccine initiation at follow-up compared to the control group.
Secondary hypothesis: 2. The intervention group will have higher vaccine completion rates (3 doses) at follow-up compared to the control group.
Detailed Description
The primary aim of the project is to increase HPV vaccine receipt rates among low-income, ethnic minority adolescents (girls and boys ages 9-17 years) in LA County. We will accomplish this goal by implementing and rigorously evaluating interventions in multiple venues that serve our target population, including the Los Angeles County Department of Public Health (LACDPH) and two large Federally Qualified Health Centers (FQHCs).
Our hypotheses are:
Primary hypothesis:
- The intervention group will have a higher rate of HPV vaccine initiation at follow-up compared to the control group.
Secondary hypothesis: 2. The intervention group will have higher vaccine completion rates (3 doses) at follow-up compared to the control group.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- None
Eligibility Criteria
- Ages
- 9 Years to 70 Years (Child, Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Recruitment Venue 1 (LACDPH) Criteria:
- •Inclusion Criteria:
- •Adult male or female
- •Current or previous user of the Los Angeles County Office of Women's Health Hotline
- •Speaks one of the hotline languages (English, Spanish, Korean, Mandarin, Cantonese, Armenian)
- •Is the medical decision-maker for a male or female adolescent aged 11-17 in his or her home
- •Adolescent has not started the HPV vaccine series
- •Current resident of Los Angeles County
Exclusion Criteria
- •Younger than 18 or older than 70 years of age
- •Not conversant in one of the hotline languages (English, Spanish, Korean, Mandarin, Cantonese, Armenian)
- •Is not the medical decision-maker for an adolescent aged 11-17 in his or her home
- •Adolescent has initiated the HPV vaccine series
- •Not a current resident of Los Angeles County
- •Recruitment Venue 2 (AltaMed) Criteria:
- •Inclusion Criteria:
- •Adolescent male or female (9-17 years)
- •Has received at least one service at the FQHC in the past 2 years
- •Exclusion Criteria:
- •Younger than 9 or older than 17 years of age
- •Has not received any services at the FQHC in the past 2 years
- •Recruitment Venue 3 (NEVHC) Criteria:
- •Inclusion Criteria:
- •Adolescent male or female (12-13 years)
- •Has received at least one service at the FQHC in the past 2 years
- •Has received no doses or 1 dose of the HPV vaccine
- •Exclusion Criteria:
- •Younger than 12 or older than 13 years of age
- •Has not received any services at the FQHC in the past 2 years
- •Has completed the 3-dose HPV vaccine
Arms & Interventions
Control
LACDPH Site: CDC-developed small media in preferred language
AltaMed Health Services Corporation Site: Usual care - Standing order for the HPV vaccine; required web-based training module for medical assistants and nurses containing basic information on HPV, the HPV vaccine, and standing order implementation
Northeast Valley Health Corporation Site: Usual care
Tailored education and referral
LACDPH Site: Tailored education and referral intervention administered at LACDPH Site
Intervention: Tailored education and referral (Behavioral)
Staff training and patient reminders
Staff training and patient reminders administered at AltaMed Health Services Corporation Site
Intervention: Staff training and patient reminders (Behavioral)
Clinic-level reminder systems
Clinic-level reminders administered at Northeast Valley Health Corporation Site
Intervention: Clinic-level reminder systems (Behavioral)
Outcomes
Primary Outcomes
HPV Vaccine Uptake
Time Frame: 3 months, 6 months
The receipt of one or more doses of the HPV vaccine
Secondary Outcomes
- HPV Vaccine Series Completion(9 months, 12 months)
Investigators
Roshan Bastani
Professor of Health Policy and Management
University of California, Los Angeles