ACTRN12616000281493已完成不适用
The use of simultaneous EEG and fMRI to monitor the effects of ketamine and midazolam on brain activity in healthy adult males
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 45 Years（—）
- 性别
- Male
入选标准
- •*Participant is willing and able to give informed consent for participation in the study
- •*In the Investigators’ opinion, is able and willing to comply with all study requirements
排除标准
- •*Cardiovascular conditions including abnormal heart rate and blood pressure checked at screening.
- •*Participants who have participated in another research study involving an investigational product in the past 12 weeks.
- •*History of psychosis or personality disorder.
- •*Any unstable medical or neurologic condition.
- •*Substance abuse or dependence in previous 6 months.
- •*Any history of abuse of ketamine or benzodiazepenes.
- •*Contraindication to the use of ketamine/midazolam according to manufacturer guidelines.
- •*Body-weight <50kg or >120kg.
- •*BMI <18.5 or > 30
- •* Failure of the Health Questionnaire section of the Anaesthesia assessment patient questionnaire”.
- •*Any other condition judged by the treating clinician as likely to impact on the ability of the participant to complete the study.
- •*Regular use of any medication deemed to be contraindicating as judged by the attending study physicians (e.g. benzodiazepenes / sedatives / sleeping agents / NMDA antagonists).
- •*Inability to speak or read English.
- •*Contraindications for MRI scanning
- •*Needle phobia
- •*History of claustrophobia
研究者
相似试验
尚未招募
1 期
Based on EEG and fMRI technology to investigate the transdermal acupoint stimulation mechanism researchhealthy subjectsITMCTR2200006101Xuzhou Rehabilitation Hospital
已完成
不适用
Simultaneous EEG and fMRI in a visual selective attention taskHet onderzoek is basaal en er werken alleen gezonde vrijwilligers meen.a.10009841NL-OMON31018niversitair Medisch Centrum Utrecht25
招募中
不适用
EEG-fMRI Experiments During Anesthesia Induction With PropofolAnesthesiaNCT06179719Technical University of Munich35
已完成
不适用
Simultaneous MEG or fMRI And INtracranial EEGHealthy VolunteersEpilepsyNCT02342938Hospices Civils de Lyon47
招募中
不适用
Integrated EEG-fMRI registratioOnderzoek naar de cognitieve-, aandachts- en geheugenprocessen bij gezonde vrijwilligersMemory and emotion processesNL-OMON35821Erasmus MC, Universitair Medisch Centrum Rotterdam20