NL-OMON44052
Completed
Not Applicable
Walking-induced motor fatigability in Multiple Sclerosis: a pilot study on underlying mechanisms and the feasibility of sequential resistance and walking-specific endurance training - Walking-induced motor fatigability in MS / MS-walk-I
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- MS
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 20
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Inclusion criteria
- •\- Definite MS
- •\- Age \>\= 18
- •\- Complain of early occurring fatigue or reduced walking speed during prolonged walking.
- •\- Able to walk continuously for 12 minutes without walking aids
Exclusion Criteria
- •Exclusion criteria
- •\- Other medical conditions that affect gait (e.g. amputation).
- •\- Serious comorbidities precluding high\-intensity exercise training
- •\- Already participating in a high intensity (\>\=2 per week), guided exercise protocol.
- •\- Pregnancy, given birth previous 6 months, or active pregnancy wish \< 6 months
- •\- Use of (dal)fampridine (i.e. fampyra®).
- •\- Use of heart rate regulating medication (i.e. Beta\-blockers)
- •\- MS exacerbation \<\= 3 months
Outcomes
Primary Outcomes
Not specified
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