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Onderzoek naar het voorkómen van nierfalen na levertransplantatie door aanpassing van de afweerremmende middelen.

Conditions
English: Advagraf, liver transplantation, optimizing immunosuppressive therapyDutch:Advagraf, levertransplantatie, optimaliseren immunosuppressieve therapie, effectiviteit en veiligheid
Registration Number
NL-OMON26731
Lead Sponsor
Foundation for Liver and Gastrointestinal Research (SLO)Department of Gastroenterology & HepatologyErasmus Medical Center Rotterdam‘s Gravendijkwal 230, Room HA 2043015 CE Rotterdam, The NetherlandsTel: +31 10 703 5942 Fax: +31 10 436 5916
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
196
Inclusion Criteria

1. Primary liver transplantation or retransplantation within 14 days after first transplantation;

2. Use of Advagraf at least 2 weeks prior to randomization;

Exclusion Criteria

1. Treatment with investigational drugs within 3 months before start of therapy;

2. Multi organ transplantation;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Percentage of patients with cGFR < 60ml/min at 36 months after transplantation.
Secondary Outcome Measures
NameTimeMethod
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