Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China

• Conditions: Irritable Bowel Syndrome

• Registration Number: NCT01060527
• Lead Sponsor: Health Science Center of Xi'an Jiaotong University

Brief Summary

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have conceptualized the faecal supernatants of diarrhoea-predominant IBS have a substantially higher serine protease activity, while in china,almost no studies have reported about protease activity in IBS.

Detailed Description

Not available

Study Timeline

• Status Verified: 2010-01
• Study Start: 2010-01
• Study First Submitted: 2010-02-01
• Study First Submitted QC: 2010-02-01
• Last Update Submitted: 2010-02-01
• Study First Posted: 2010-02-02
• Last Update Posted: 2010-02-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients fulfilling the Rome III criteria for IBS participated in the study -

Exclusion Criteria

• Organic gastrointestinal disorders were excluded by detailed blood and stool analyses, serological assays and colonoscopy.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified