SWE Liver Stiffness as a Predictor of Progression of Chronic Liver Diseases
Completed
- Conditions
- Liver Fibroses
- Registration Number
- NCT03389152
- Lead Sponsor
- SuperSonic Imagine
- Brief Summary
This study is a multicenter individual patient-based meta-analysis that will assess the performances of liver stiffness measurements performed with supersonic shear imaging shearwave elastography (SSI-SWE) in patients with liver fibrosis to predict progression of chronic liver disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2148
Inclusion Criteria
- Patients who had received a liver ultrasound exam at baseline for a suspected chronic fibrotic liver disease of viral and/or steatotic origin,
- Patients who had reached the age of majority in their countries, at baseline,
- Patients with a baseline liver biopsy for histological evaluation of liver fibrosis with a length ≥ 15 mm paraffin sections (except if cirrhosis),
- Patients for whom a minimum length of clinical follow-up from baseline of 1 year had been recorded
Exclusion Criteria
- Cause of chronic liver disease other than viral, ALD or NAFLD ( hemochromatosis, autoimmune hepatitis, biliary tract disease intrahepatic...)
- Any systemic, viral hepatitis and HIV co-infection
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Liver disease progression rate Minimum of 28 days follow-up Clinical signs of liver decompensation
Mortality rate Minimum of 28 days follow-up Patient's death
- Secondary Outcome Measures
Name Time Method