Shock Wave Versus Traditional Physical Therapy for Adult Chronic Knee Osteoarthritis: A Prospective Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Change in pain intensity
研究概览
简要总结
This study aims to compare the effectiveness of extracorporeal shock wave therapy (ESWT) versus structured therapeutic exercise in patients with chronic knee osteoarthritis (KOA), with respect to pain reduction and improvement of knee function.
详细描述
Knee osteoarthritis (KOA) is a highly prevalent chronic degenerative joint disease characterized by progressive cartilage loss, chronic pain, stiffness, functional disability, and reduced quality of life in adults, particularly the elderly.
Extracorporeal shock wave therapy (ESWT) has emerged as a non-invasive physical modality that delivers acoustic pressure waves to musculoskeletal tissues, stimulating biological responses such as enhanced microcirculation, anti-inflammatory cytokine modulation, neovascularization, cartilage and bone repair processes, and decreased pain transmission.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults ≥ 40 years with clinical and radiographic diagnosis of chronic knee osteoarthritis (KOA) (Kellgren-Lawrence grade II-III).
- •Both sexes.
- •Persistent knee pain ≥ 3 months.
- •Ability to provide consent and participate in interventions.
排除标准
- •Prior knee surgery within last 6 months.
- •Intra-articular injections in the last 3 months.
- •Systemic inflammatory arthritis or other neurological conditions affecting gait.
研究组 & 干预措施
Exercise Therapy Group
Patients will undergo a structured exercise therapy program.
干预措施: Exercise therapy program (Other)
ESWT Group
Patients will receive extracorporeal shock wave therapy.
干预措施: Extracorporeal shock wave therapy (Other)
结局指标
主要结局
Change in pain intensity
时间窗: 5-week after intervention
Change in pain intensity will be assessed using the Visual Analogue Scale (VAS) which is a 10-cm horizontal line used to measure pain intensity, ranging from (0) "no pain" to (10) "worst imaginable pain".
次要结局
- Stiffness assessment(5-week after intervention)
- Assessment of physical function(5-week after intervention)
- Knee range of motion(5-week after intervention)
- Incidence of adverse events(5-week after intervention)
研究者
Magdy Mohamed Aly Shabana
Associate Professor in Orthopedic, Physical Therapy
German International University