Comparison of the efficacy of oral Acetaminophen and oral Ibuprofen for treatment of preterm with patent ductus arteriosus
Phase 3
- Conditions
- Q25.0Patent ductus arteriosus (PDA).Patent ductus arteriosus
- Registration Number
- IRCT20211010052715N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Parent's consent to participate in the study
Gestational age 26 to 37 weeks
Diagnosis of ductus arteriosus based on echocardiographic evidence at 24 to 72 hours after birth
Exclusion Criteria
Premature newborn with fever and seizure
Life-threatening infections,
Clinical or radiographic evidence of necrotizing enterocolitis
Evidence of bleeding
Platelets less than 50,000 per ml
Liver failure
Congenital brain-neurological disorders,
Metabolic and genetic syndromes
Pulmonary hypoplasia syndrome
Congenital heart anomalies or other fatal abnormalities
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PDA size. Timepoint: Before and after the intervention. Method of measurement: Echocardiography by pediatiric's cardiologist .
- Secondary Outcome Measures
Name Time Method