ADESPI: Adherence to Spiriva® in Patients With COPD (Chronic Obstructive Pulmonary Disease), Measured by Morisky-8 (MMAS-8) Scale, in Routine Medical Practice
- Conditions
- Pulmonary Disease, Chronic Obstructive
- Interventions
- Procedure: Education
- Registration Number
- NCT01388166
- Lead Sponsor
- Boehringer Ingelheim
- Brief Summary
The objective of this observational study is to collect and evaluate data on medication adherence of patients on maintenance COPD therapy with long-acting anticholinergic (e.g. Spiriva® delivered by HandiHaler® or Respimat®) using the MMAS-8 questionnaire.
- Detailed Description
Purpose:
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1253
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients with COPD Education -
- Primary Outcome Measures
Name Time Method Mean Change of Morisky Medication Adherence Scale -8 (MMAS-8) Score at the End of the Educational Period After 6 Months From Baseline Baseline and 6 months The MMAS-8 scale is a recognized indicator of medication adherence, consisting of 8 questions with a sum score ranging between 0 and 8 points. The higher score indicates higher adherence to the prescribed therapy recommendation. It has been agreed that the score of 8 could be categorized as having high adherence, score between 6 and 7 as medium adherence and scores of 5 and less as low adherence. The change is presented as the score on visit 3 minus the score at baseline. Therefore, a positive change score reflects an improvement in the adherence.
- Secondary Outcome Measures
Name Time Method Mean Change of Morisky Medication Adherence Scale -8 (MMAS-8) Score at the End of the Observational Period After 12 Months From End of Educational Period After 6 Months. 6 months and 12 months The MMAS-8 scale is a recognized indicator of medication adherence, consisting of 8 questions with a sum score ranging between 0 and 8 points. The higher score indicates higher adherence to the prescribed therapy recommendation. It has been agreed that the score of 8 could be categorized as having high adherence, score between 6 and 7 as medium adherence and scores of 5 and less as low adherence. The change is presented as the score on visit 4 minus the score at visit 3. Therefore, a positive change score reflects an improvement in the adherence.
Mean Change of Morisky Medication Adherence Scale -8 (MMAS-8) Score at the End of the Observational Period After 12 Months From Baseline 12 months and baseline The MMAS-8 scale is a recognized indicator of medication adherence, consisting of 8 questions with a sum score ranging between 0 and 8 points. The higher score indicates higher adherence to the prescribed therapy recommendation. It has been agreed that the score of 8 could be categorized as having high adherence, score between 6 and 7 as medium adherence and scores of 5 and less as low adherence. The change is presented as the score on visit 4 minus the score at visit 1 (baseline). Therefore, a positive change score reflects an improvement in the adherence.
Trial Locations
- Locations (90)
Boehringer Ingelheim Investigational Site 55
🇭🇺Cegléd, Hungary
Boehringer Ingelheim Investigational Site 90
🇭🇺Budapest, Hungary
Boehringer Ingelheim Investigational Site 36
🇸🇰Lucenec, Slovakia
Boehringer Ingelheim Investigational Site 35
🇸🇰Lucenec, Slovakia
Boehringer Ingelheim Investigational Site 27
🇸🇰Topolcany, Slovakia
Boehringer Ingelheim Investigational Site 2
🇸🇰Senec, Slovakia
Boehringer Ingelheim Investigational Site 7
🇸🇰Trnava, Slovakia
Boehringer Ingelheim Investigational Site 62
🇭🇺Budapest, Hungary
Boehringer Ingelheim Investigational Site 63
🇭🇺Budapest, Hungary
Boehringer Ingelheim Investigational Site 67
🇭🇺Budapest, Hungary
Boehringer Ingelheim Investigational Site 68
🇭🇺Budapest, Hungary
Boehringer Ingelheim Investigational Site 89
🇭🇺Budapest, Hungary
Boehringer Ingelheim Investigational Site 59
🇭🇺Kistokaj, Hungary
Boehringer Ingelheim Investigational Site 74
🇭🇺Komló, Hungary
Boehringer Ingelheim Investigational Site 72
🇭🇺Mosonmagyaróvár, Hungary
Boehringer Ingelheim Investigational Site 53
🇭🇺Nyíregyháza, Hungary
Boehringer Ingelheim Investigational Site 83
🇭🇺Nyírbátor, Hungary
Boehringer Ingelheim Investigational Site 73
🇭🇺Pécs, Hungary
Boehringer Ingelheim Investigational Site 87
🇭🇺Szeged, Hungary
Boehringer Ingelheim Investigational Site 76
🇭🇺Tapolca, Hungary
Boehringer Ingelheim Investigational Site 70
🇭🇺Törökszentmiklós, Hungary
Boehringer Ingelheim Investigational Site 75
🇭🇺Várpalota, Hungary
Boehringer Ingelheim Investigational Site 86
🇭🇺Érd, Hungary
Boehringer Ingelheim Investigational Site 41
🇸🇰Bardejov, Slovakia
Boehringer Ingelheim Investigational Site 42
🇸🇰Bardejov, Slovakia
Boehringer Ingelheim Investigational Site 32
🇸🇰Bojnice, Slovakia
Boehringer Ingelheim Investigational Site 1
🇸🇰Bratislava, Slovakia
Boehringer Ingelheim Investigational Site 9
🇸🇰Bratislava, Slovakia
Boehringer Ingelheim Investigational Site 26
🇸🇰Hurbanovo, Slovakia
Boehringer Ingelheim Investigational Site 13
🇸🇰Kosice, Slovakia
Boehringer Ingelheim Investigational Site 15
🇸🇰Kosice, Slovakia
Boehringer Ingelheim Investigational Site 25
🇸🇰Levice, Slovakia
Boehringer Ingelheim Investigational Site 64
🇭🇺Dunakeszi, Hungary
Boehringer Ingelheim Investigational Site 78
🇭🇺Esztergom, Hungary
Boehringer Ingelheim Investigational Site 65
🇭🇺Mátraháza, Hungary
Boehringer Ingelheim Investigational Site 82
🇭🇺Szombathely, Hungary
Boehringer Ingelheim Investigational Site 79
🇭🇺Tatabánya, Hungary
Boehringer Ingelheim Investigational Site 66
🇭🇺Budapest, Hungary
Boehringer Ingelheim Investigational Site 77
🇭🇺Dunaújváros, Hungary
Boehringer Ingelheim Investigational Site 52
🇭🇺Hajdúnánás, Hungary
Boehringer Ingelheim Investigational Site 80
🇭🇺Zalaegerszeg, Hungary
Boehringer Ingelheim Investigational Site 4
🇸🇰Myjava, Slovakia
Boehringer Ingelheim Investigational Site 6
🇸🇰Trnava, Slovakia
Boehringer Ingelheim Investigational Site 49
🇸🇮Golnik, Slovenia
Boehringer Ingelheim Investigational Site 61
🇭🇺Budapest, Hungary
Boehringer Ingelheim Investigational Site 58
🇭🇺Baja, Hungary
Boehringer Ingelheim Investigational Site 71
🇭🇺Komárom, Hungary
Boehringer Ingelheim Investigational Site 88
🇭🇺Nyíregyháza, Hungary
Boehringer Ingelheim Investigational Site 69
🇭🇺Szigetszentmiklós, Hungary
Boehringer Ingelheim Investigational Site 57
🇭🇺Tiszaújváros, Hungary
Boehringer Ingelheim Investigational Site 29
🇸🇰Banská Bystrica, Slovakia
Boehringer Ingelheim Investigational Site 17
🇸🇰Gelnica, Slovakia
Boehringer Ingelheim Investigational Site 14
🇸🇰Kosice, Slovakia
Boehringer Ingelheim Investigational Site 33
🇸🇰Lucenec, Slovakia
Boehringer Ingelheim Investigational Site 23
🇸🇰Nitra, Slovakia
Boehringer Ingelheim Investigational Site 47
🇸🇰Povazská Bystrica, Slovakia
Boehringer Ingelheim Investigational Site 3
🇸🇰Senica, Slovakia
Boehringer Ingelheim Investigational Site 37
🇸🇰Stropkov, Slovakia
Boehringer Ingelheim Investigational Site 85
🇭🇺Békéscsaba, Hungary
Boehringer Ingelheim Investigational Site 51
🇭🇺Debrecen, Hungary
Boehringer Ingelheim Investigational Site 56
🇭🇺Edelény, Hungary
Boehringer Ingelheim Investigational Site 60
🇭🇺Gyöngyös, Hungary
Boehringer Ingelheim Investigational Site 84
🇭🇺Szentes, Hungary
Boehringer Ingelheim Investigational Site 28
🇸🇰Galanta, Slovakia
Boehringer Ingelheim Investigational Site 12
🇸🇰Kosice, Slovakia
Boehringer Ingelheim Investigational Site 44
🇸🇰Martin, Slovakia
Boehringer Ingelheim Investigational Site 31
🇸🇰Prievidza, Slovakia
Boehringer Ingelheim Investigational Site 34
🇸🇰Rimavská Sobota, Slovakia
Boehringer Ingelheim Investigational Site 10
🇸🇰Roznava, Slovakia
Boehringer Ingelheim Investigational Site 43
🇸🇰Zilina, Slovakia
Boehringer Ingelheim Investigational Site 81
🇭🇺Kaposvár, Hungary
Boehringer Ingelheim Investigational Site 54
🇭🇺Kecskemét, Hungary
Boehringer Ingelheim Investigational Site 16
🇸🇰Kosice, Slovakia
Boehringer Ingelheim Investigational Site 38
🇸🇰Michalovce, Slovakia
Boehringer Ingelheim Investigational Site 18
🇸🇰Spisská Nová Ves, Slovakia
Boehringer Ingelheim Investigational Site 8
🇸🇰Trnava, Slovakia
Boehringer Ingelheim Investigational Site 46
🇸🇰Trstená, Slovakia
Boehringer Ingelheim Investigational Site 45
🇸🇰Cadca, Slovakia
Boehringer Ingelheim Investigational Site 22
🇸🇰Nitra, Slovakia
Boehringer Ingelheim Investigational Site 24
🇸🇰Nitra, Slovakia
Boehringer Ingelheim Investigational Site 30
🇸🇰Nová Bana, Slovakia
Boehringer Ingelheim Investigational Site 48
🇸🇰Nové Mesto n. Váhom, Slovakia
Boehringer Ingelheim Investigational Site 19
🇸🇰Nové Zámky, Slovakia
Boehringer Ingelheim Investigational Site 20
🇸🇰Nové Zámky, Slovakia
Boehringer Ingelheim Investigational Site 21
🇸🇰Nové Zámky, Slovakia
Boehringer Ingelheim Investigational Site 5
🇸🇰Piestany, Slovakia
Boehringer Ingelheim Investigational Site 39
🇸🇰Presov, Slovakia
Boehringer Ingelheim Investigational Site 40
🇸🇰Presov, Slovakia
Boehringer Ingelheim Investigational Site 11
🇸🇰Rimavská Sobota, Slovakia
Boehringer Ingelheim Investigational Site 50
🇸🇮Maribor-Pohorje, Slovenia