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Clinical Trials/NCT03278301
NCT03278301
Completed
Not Applicable

A Multicenter Post-Market Registry for the Evaluation of the CorPath® GRX System Effectiveness in Percutaneous Coronary Interventions

Corindus Inc.20 sites in 4 countries952 target enrollmentAugust 27, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Coronary Artery Disease
Sponsor
Corindus Inc.
Enrollment
952
Locations
20
Primary Endpoint
Clinical Success
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

To collect data on the routine patterns of use, safety and effectiveness, including the clinical and technical performance of the CorPath GRX System, in the delivery and manipulation of coronary guidewires and stent/balloon catheters, and manipulation of guide catheters during PCI procedures.

Detailed Description

This is a single-arm, open-label, multi-center patient registry of the CorPath GRX System to examine its performance during PCI procedures and patient outcomes through 72 hours post-procedure or hospital discharge, whichever occurs first.

Registry
clinicaltrials.gov
Start Date
August 27, 2017
End Date
February 6, 2020
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Candidates will be included in the study only if all of the following conditions are met:
  • Age ≥18 years;
  • Patients with coronary artery disease with clinical indication for PCI;
  • Patient deemed appropriate for robotic-assisted PCI; and
  • The subject has been informed of the nature of the study, agrees to its provisions and has provided written informed consent.

Exclusion Criteria

  • Candidates will be excluded from the study if any of the following conditions are present:
  • Failure/inability/unwillingness to provide informed consent; or
  • The investigator determines that the patient or the coronary anatomy is not suitable for robotic-assisted PCI.

Outcomes

Primary Outcomes

Clinical Success

Time Frame: Discharge or 72 hours post intervention, whichever comes first.

Less than 30% residual stenosis (visual estimate) post PCI in the lesion(s) treated with the CorPath GRX System, without in-hospital major adverse coronary events (MACE).

Technical Success

Time Frame: Procedure

Defined as successful completion of the robotic-assisted PCI absent unplanned conversion to manual for guidewire or balloon/stent catheter inability to navigate vessel anatomy or poor guide catheter support.

Secondary Outcomes

  • Overall Procedure Time(Procedure)
  • Fluoroscopy Time(Procedure)
  • Patient Radiation Exposure(Procedure)
  • PCI Procedure Time(Procedure)

Study Sites (20)

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