Comparing two oxygen delivery techniques in patients with breathing difficulty
Not Applicable
- Conditions
- Health Condition 1: J80- Acute respiratory distress syndrome
- Registration Number
- CTRI/2020/08/027176
- Lead Sponsor
- Dr D Vimal Bhardwaj
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patient aged more than or equal to 18 years, both the genders in the emergency and medical/surgical intensive care units
2. Requiring CPAP/HFNC support
3. Subject or legally authorized representative/patient relative willing
to provide written informed consent.
Exclusion Criteria
1.Need for direct admission to the intensive care unit for mechanical ventilation
2. Unconscious or patient with drowsiness
3. Pneumothorax
4. Carbon dioxide pressure (pCO2) >45 mmHg in venous blood gas (VBG)
5. Haemodynamic instability (MAP <65 mmHg)
6. Pregnant women
7. Severe head/neck and facial injuries
8. Tracheostomy on admission
9. Patient enrolled in another study
10. Inability to comprehend the study content and give informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of patients who did not progress to mechanical ventilation <br/ ><br>Timepoint: 28 days
- Secondary Outcome Measures
Name Time Method Days alive withinTimepoint: 28 days and 180 days;Frequency of carbon dioxide rebreathingTimepoint: 28 days;Frequency of endotracheal intubationTimepoint: 28 days;Patient comfortTimepoint: 24 hours after randomisation;SpO2/FiO2 -ratioTimepoint: 1 hour after randomisation