What is the potential diagnostic value of distention and intima-media thickness measurement for the early detection of endofibrosis and is there a link between the development of endofibrosis an the coagulation activation potential of the blood?
Completed
- Conditions
- EndofibrosisIliacal fibrosis10003216
- Registration Number
- NL-OMON44935
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 67
Inclusion Criteria
Controle population: minimal 18 years old and max 35 years old - mentally capable - male
Population with endofibrosis: - minimal 18 years old and maximal 35. - mentally capable - negative MRA and echo doppler within the last 12 months - complaining of lower limb ischemia during exercise.
Population with endofibrosis: - minimal 18 years old and maximal 35. - mentally capable - complaining of lower limb ischemia during exercise - confirmed endofibrosis by Magnetic Resonance Angiography.
Exclusion Criteria
all population: diagnosed with an cardiovascular disease, operation on the a. iliacal communis or a. iliacal externa, BMI > 30, <18 years old.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Determining the IMT of the common iliac artery wall.<br /><br>Determining the distension of the pelvic arterial wall.<br /><br>Determine coagulation parameters</p><br>
- Secondary Outcome Measures
Name Time Method <p>n.v.t</p><br>