Peritoneal Dialysis Pilot Study: Evaluating Polyethylene Glycol (PEG) for Constipation

Phase 4

Completed

• Conditions: Peritoneal Dialysis Complication; Constipation

• Registration Number: NCT03148002
• Lead Sponsor: Nova Scotia Health Authority

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-3-14
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion Criteria:<br><br> - All patients in the peritoneal dialysis program in Nova Scotia who are currently<br> taking laxatives.<br><br>Exclusion Criteria:<br><br> - Allergy or intolerance to any of the study laxatives (PEG, senna, lactulose);<br> cognitive impairment or inability to document symptoms; known or suspected<br> gastrointestinal obstruction or ileus; known or planned pregnancy; no laxative use<br> in the last 3 months.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of constipation treatment success

Secondary Outcome Measures

Name	Time	Method
Number of patients with laxative related adverse effects.;Mean change from baseline on the PAC-SYM questionnaire;Mean change from baseline on the PAC-QOL questionnaire;Incidence of peritoneal dialysis treatment failure requiring intervention