Investigation of safety, tolerability and pharmacokinetic properties of single subcutaneous doses of NNC0194-0499 in Japanese and non-Asian male subjects
Phase 1
- Conditions
- non-alcoholic steatohepatitis
- Registration Number
- JPRN-jRCT2071200100
- Lead Sponsor
- Sudoh Yuki
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 42
Inclusion Criteria
1. For Japanese subjects only, both parents of Japanese descent. For non-Asian subjects only, both parents of non-Asian descent.
2. Body mass index (BMI) between 23.0 and 34.9 kg/m2 (both inclusive). Overweight should be due to excess adipose tissue, as judged by the investigator.
3. Body weight >= 60 kg.
4. Considered by the investigator to be generally healthy based on the medical history, physical examination, and the results of vital signs, ECG, and clinical laboratory tests performed during the screening visit.
Exclusion Criteria
Any disorder which in the opinion of investigator might jeopardise subject safety or compliance with the protocol.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method