The relationship of Blood lactate levels and Ratio between the Veno-arterial Carbon Dioxide Difference and the Arterial‐venous Oxygen Difference in patients undergoing elective cardiac surgery: Prospective cohort study

Not Applicable

Completed

• Conditions: Cardiac disease; Veno- arterial CO2 difference and Arterial‐venous O2 difference ratio, central venous oxygen saturation, Cardiac surgery, Blood lactate, Cardiopulmonary bypass

• Registration Number: TCTR20200417002
• Lead Sponsor: Maharaj nakorn chiang mai hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-02-04
• Study Start: 2020-04-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

-Elective cardiac surgery under cardiopulmonary bypass assistance
-Ages >_ 18 years
-American Society of Anesthesiologists (ASA) physical status II-III
-Required central venous pressure catheter or pulmonary artery catheter insertion
-Consent to participate in research

Exclusion Criteria

-Co-existing pulmonary disease: Chronic obstructive pulmonary disease with Forced Expiratory Volume in 1 second (FEV1) < 50%
-Co-existing liver disease
-End-stage renal disease
-Patients with sepsis
-Pregnant woman
-Thoracic aortic surgery

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Veno-arterial CO2 difference and Arterial‐venous O2 difference ratio and blood lactate level After induction of anesthesia, Immediately after ICU admission, 6 hr after ICU admission Blood sampling

Secondary Outcome Measures

Name	Time	Method
Veno-arterial CO2 difference and Arterial‐venous O2 difference ratio, perfusion index After induction of anesthesia, Immediately after ICU admission, 6 hr after ICU admission Blood sampling ,Veno-arterial CO2 difference and Arterial‐venous O2 difference ratio,central venous oxygen satura After induction of anesthesia, Immediately after ICU admission, 6 hr after ICU admission Blood sampling ,Perioperative complications After induction of anesthesia, Immediately after ICU admission, 6 hr after ICU admission Blood sampling ,Mortality in 1 month After induction of anesthesia, Immediately after ICU admission, 6 hr after ICU admission Blood sampling