ACTRN12622000349741招募中2 期
'One injection vs. three': Evaluation of the safety and tolerability of a single, high dose subcutaneous infusion of benzathine penicillin G for treatment of syphilis (SCIP Syphilis)
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •(a)Males and non-pregnant females aged older than 18 years
- •(b)Diagnosis of syphilis infection (made by a medical practitioner) AND requiring treatment with BPG in the form of Bicillin® L-A. This is defined as follows:
- •i.Positive treponemal serology (Total antibody AND TPPA)
- •ii.Primary syphilis (diagnosed clinically) with PCR confirmation of T. pallidum
- •(c)No prior documented allergy to penicillin.
- •(d)No history of anaphylactic reaction to cephalosporin antibiotics.
- •(e)Participants who are considered likely to adhere to the trial guidelines for the duration of the trial and are willing and deemed reliable to attend follow up appointments as outlined in the protocol.
- •(f)Able to provide informed consent in accordance with Good Clinical Practice.
排除标准
- •(a)Pregnant or breastfeeding females
- •(b)Diagnosis of neurosyphilis (CNS, otic or optic syphilis) made by a medical practitioner
- •(c)Known hypersensitivity or contraindication to use of penicillin.
- •(d)Existing dermatological conditions or other abnormalities (e.g., extensive scarring) that may affect skin integrity at the site of injection, especially abdomen or lateral hips.
- •(e)Presence of significant co-morbidities which is likely to impact patient’s participation the study, as assessed by a medical practitioner
研究者
相似试验
已完成
1 期
A single centre, double blind, randomised, parallel group, single and multiple dose, safety and tolerability, pharmacokinetic study of R131-2 vaginal soft gel capsule in healthy women volunteersCervical neoplasiaCondyloma acuminatumInfection - Sexually transmitted infectionsACTRN12621001487808Zenith Technology Corporation Limited12
已完成
不适用
The comparison of single injection with multiple injection in local anesthesia in patients undergone upper limp surgeryupper limb injuries.Injury of arm NOSIRCT2012103011326N1Hamedan University of Medical Sciences40
已完成
不适用
Safety and efficacy of single-dose and triple-dose albendazole and mebendazole against soil-transmitted helminth infections in humansISRCTN47375023Swiss Tropical Institute (STI) (Switzerland)370
招募中
2 期
Evaluation of an injectable solution with the brand name ®Embella in order to reduce submental fat.Submental fat.IRCT20190210042676N29Zist orchid pharmed Company20
尚未招募
3 期
Comparison between effectiveness of injection of anesthetic agents to provide painfree surgery for your affected arm by two different methods - under ultrasound guidance, injecting drugs at the centre of the nerves of your arm and at 3 different places surrounding the nerves of your arm.CTRI/2021/05/033391nil