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Clinical Trials/NCT05255562
NCT05255562
Completed
Not Applicable

Comparison of the Effects of Ultrasound-Guided Combined Serratus Anterior Plane Block and Thoracic Paravertebral Block on Postoperative Acute Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery

Atatürk Chest Diseases and Chest Surgery Training and Research Hospital1 site in 1 country60 target enrollmentFebruary 15, 2022

Overview

Phase
Not Applicable
Intervention
Combined Serratus Anterior Plane Block
Conditions
Multimodal Analgesia
Sponsor
Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Enrollment
60
Locations
1
Primary Endpoint
Pain Scores
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS. Analgesic methods such as thoracic paravertebral block (TPVB), intercostal block, serratus anterior plane block (SAPB), and erector spinae plane block (ESPB) are widely used for VATS. Among these methods, ultrasound (US) guided TPVB is the most preferred method. In recent years, the frequency of application of plane blocks as a component of multimodal analgesia has been increased. ESPB and SAPB are some of them. There are two techniques for SAPB application. In Deep SAPB (DSAPB) application, a local anesthetic agent is given under the serratus anterior muscle. In the Superficial SAPB (SSAPB) application, the local anesthetic agent is given above the serratus anterior muscle. Since it is done by entering from the same point in two applications, it is possible to perform these two applications at the same time with a single needle entry. The mechanisms of regional analgesia techniques used after thoracic surgery operations are also different from each other. Therefore, it may be possible to obtain a more effective analgesic effect in patients by combining the mechanism of action of DSAPB and SSAPB, as in the multimodal analgesia method. This study seeks to evaluate the effect of TPVB and combined SAPB (CSAPB) after VATS.

Registry
clinicaltrials.gov
Start Date
February 15, 2022
End Date
May 16, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

Musa Zengin

Principal İnvestigator

Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • 18 to 65 years old
  • ASA physical status I-II-III
  • BMI 18 to 30 kg/m2
  • Elective video-assisted thoracoscopic surgery

Exclusion Criteria

  • Patient refusing the procedure
  • Emergency surgery
  • Chronic opioid or analgesic use

Arms & Interventions

Combined Serratus Anterior Plane Block

In patients who are planned to have combined deep and superficial serratus anterior plane block, following the visualization of the anatomical structures, the nerve block needle will be advanced via the in-plane technique beneath the serratus anterior muscles until the interfascial space was reached. After hydrodissection with 2 ml normal saline, 15 ml 0.25% bupivacaine will be injected into the area. Then, with the same needle, will be returned 1-2 cm from the deep serratus anterior area to the superficial serratus anterior area above the serratus anterior muscle and injected 2 ml normal saline for hydrodissection. Finally, 15 ml of 0.25% bupivacaine will be injected for the superficial serratus anterior block into the interfacial area.

Intervention: Combined Serratus Anterior Plane Block

Thoracic Paravertebral Block

In patients who are planned to have a thoracic paravertebral block, the needle will be advanced to the paravertebral area with ultrasound-guided in-plane technique. 30 ml of 0.25% bupivacaine will be injected into this area.

Intervention: Thoracic Paravertebral Block

Outcomes

Primary Outcomes

Pain Scores

Time Frame: 48 hours after surgery

Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 1st, 2nd, 4th, 8th, 16th, 24th and 48th hours after surgery.

Secondary Outcomes

  • Morphine Consumption(24 hours after surgery)

Study Sites (1)

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