Extubation Times in Postoperative Congenital Cardiovascular Surgeries

Completed

• Conditions: Congenital Heart Disease
• Interventions: Procedure: Congenital Cardiovascular Surgery

• Registration Number: NCT05332860
• Lead Sponsor: Bursa Yüksek İhtisas Education and Research Hospital

Brief Summary

Background: Anesthesia management in pediatric cardiac surgeries focuses on reducing morbidity and mortality, early mobilization and discharge, using health resources sparingly and increasing the quality of life of patients. The duration of postoperative mechanical ventilation is one of the most important factors affecting the process after pediatric cardiac surgery. Besides the view that postoperative mechanical ventilation is safe, there are opposing views that it causes an increase in complications; It caused disagreements about extubation times. In our study, we aimed to investigate the factors affecting extubation times after pediatric cardiac surgery.

Methods: 72 ASA≥III pediatric patients undergoing cardiac surgery with cardiopulmonary bypass were included in our study. The patients were divided into 3 groups according to their extubation time. Those that were extubated in the operating room (OR) or in 6 hours after surgery (Immediate Extubation or IE), those that were extubated within 6-48 hours of admission to the ICU (Early Extubation or EE) and those that were extubated sometime after 48 hours or not extubated (Delayed Extubation or DE). Many variables of preoperative, peroperative and postoperative periods were recorded to see which factors correlated with extubation times.

Detailed Description

Children with critical congenital heart disease may need surgical or interventional procedures at some point in their lives.In pediatric cardiac anesthesia, it is important to reduce the need for postoperative mechanical ventilation in order to minimize morbidity, provide optimal vital functions, and reduce unnecessary use of health resources. Researchers aimed to examine the relationships of perioperative and postoperative hemodynamics, laboratory, oxygenation parameters and demographic data with extubation times in pediatric cardiac surgery cases taken in the hospital.

Study Timeline

• Study Start: 2020-05-01
• Primary Completion: 2020-12-31
• Study Completion: 2021-02-15
• Study First Submitted: 2022-03-22
• Study First Submitted QC: 2022-04-11
• Study First Posted: 2022-04-18
• Status Verified: 2023-03
• Last Update Submitted: 2023-03-28
• Last Update Posted: 2023-03-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

• elective or emergency patients
• aged 0-18 who are scheduled for congenital heart surgery

Exclusion Criteria

-in patients who died during the operation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Immediate Extubation or IE	Congenital Cardiovascular Surgery	patients were extubated in the operating room (OR) or in 6 hours after surgery
Early Extubation or EE	Congenital Cardiovascular Surgery	patients were extubated within 6-48 hours of admission to the ICU
Delayed Extubation or DE	Congenital Cardiovascular Surgery	patients were extubated sometime after 48 hours or not extubated

Primary Outcome Measures

Name	Time	Method
extubation times	10 days after surgery	postoperative mechanical ventilation times

Secondary Outcome Measures

Name	Time	Method
mortality	on 10 days	mortality rates of groups

Trial Locations

Locations (1)

Bursa Training and Research Hospital; 🇹🇷 Bursa, Turkey