The effects of Celecoxib in the treatment of postpartum depression with mild intensity to the average

Phase 2

• Conditions: O90.6; Postpartum depression.; Postpartum mood disturbance

• Registration Number: IRCT20090117001556N125
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 15 June 2020

Recruitment & Eligibility

• Status: Pending
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

Age between 18 to 45
Having mild to moderate depression according to Hamilton Depression Rating Scale (HAM-D)

Exclusion Criteria

Having severe depression according to Hamilton Depression Rating Scale (HAM-D or HDRS)
Addiction to drugs
Addiction to alcohol
Presence of Thyroid disease
Receiving any antidepressant medications during past one month prior to the trial
Receiving Electroconvulsive therapy during past two months prior to the trial
Any other diagnosis according to axis-1, DSM-5
Having a risk of suicide based on doctor's clinical judgement or having a score of >2 in suicide item of Hamilton Depression Rating Scale (HAM-D or HDRS)
Concomitant use of medications that increase the risk of gastrointestinal bleeding
Presence of cardiovascular disease
Pregnant and lactating women
Risk of child murder

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of depression. Timepoint: Baseline and weeks 2, 4, 6, and 8. Method of measurement: By Hamilton Depression Rating Scale (HAM-D or HDRS).